* denotes equal contributions.

2026

Halo: a pretrained model for whole-cell segmentation from nuclei images in spatial transcriptomics

Xingyuan Zhang, Haotian Zhuang, Zhicheng Ji

Briefings in Bioinformatics 2026

Halo: a pretrained model for whole-cell segmentation from nuclei images in spatial transcriptomics

Xingyuan Zhang, Haotian Zhuang, Zhicheng Ji

Briefings in Bioinformatics 2026

Trajectory-guided dimensionality reduction for multi-sample single-cell RNA-seq data reveals biologically relevant sample-level heterogeneity

Haotian Zhuang, Xin Gai, Anru R. Zhang, Wenpin Hou, Zhicheng Ji, Pixu Shi

Bioinformatics 2026

Trajectory-guided dimensionality reduction for multi-sample single-cell RNA-seq data reveals biologically relevant sample-level heterogeneity

Haotian Zhuang, Xin Gai, Anru R. Zhang, Wenpin Hou, Zhicheng Ji, Pixu Shi

Bioinformatics 2026

PreTSA: computationally efficient modeling of temporal and spatial gene expression patterns

Haotian Zhuang, Zhicheng Ji

Genome Biology 2026

PreTSA: computationally efficient modeling of temporal and spatial gene expression patterns

Haotian Zhuang, Zhicheng Ji

Genome Biology 2026

2025

Identifying cell-type-specific spatially variable genes with ctSVG

Haotian Zhuang, Xinyi Shang, Wenpin Hou, Zhicheng Ji

Genome Biology 2025

Recommended for multiple use cases in an independent benchmarking study published in Briefings in Bioinformatics.

Identifying cell-type-specific spatially variable genes with ctSVG

Haotian Zhuang, Xinyi Shang, Wenpin Hou, Zhicheng Ji

Genome Biology 2025

Recommended for multiple use cases in an independent benchmarking study published in Briefings in Bioinformatics.

2024

Assessment of treatment effect heterogeneity for multi-regional randomized clinical trials

Haotian Zhuang, Xiaofei Wang, Stephen L. George

Statistics in Biopharmaceutical Research 2024

Assessment of treatment effect heterogeneity for multi-regional randomized clinical trials

Haotian Zhuang, Xiaofei Wang, Stephen L. George

Statistics in Biopharmaceutical Research 2024

2022

findPC: An R package to automatically select the number of principal components in single-cell analysis

Haotian Zhuang, Huimin Wang, Zhicheng Ji

Bioinformatics 2022

findPC: An R package to automatically select the number of principal components in single-cell analysis

Haotian Zhuang, Huimin Wang, Zhicheng Ji

Bioinformatics 2022