Fit the gene expression along pseudotime values (binning)

Fit the gene expression along pseudotime values (binning)

Usage

temporalFit_bin(expr, pseudotime, knot = 0, maxknotallowed = 10, numbin = 10)

Arguments

expr

The normalized gene expression matrix. Rows represent genes and columns represent cells

pseudotime

The vector of user-provided pseudotime values

knot

Number of knots (0 by default) or "auto" for automatic selection

maxknotallowed

A user-defined maximum number of knots (10 by default)

numbin

Number of bins (10 by default)

Value

The fitted expression matrix. Rows represent genes and columns represent cells