Fit the gene expression along pseudotime values
Usage
temporalFit(expr, pseudotime, knot = F, maxknotallowed = 10)
Arguments
- expr
The normalized gene expression matrix. Rows represent genes and columns represent cells
- pseudotime
The vector of user-provided pseudotime values
- knot
Whether to select the optimal number of knots automatically
- maxknotallowed
A user-defined maximum number of knots (10 by default)
Value
The fitted expression matrix. Rows represent genes and columns represent cells